
microRNA Biogenesis and Function: From Drosha to RISC in Gene Silencing
Introduction to microRNA microRNAs (miRNAs) are endogenous, non-coding RNA molecules approximately 21–23 nucleotides in length. They play a critical role in post-transcriptional regulation of gene expression in eukaryotic cells. Unlike messenger RNAs (mRNAs), miRNAs do not encode proteins but function…